Drug Name:GnRH analogues
Drug Class:Hormonal therapy
Mechanism of Action:
  • Bind to GnRH receptors in the pituitary gland
  • Reduce the secretion of luteinizing hormone (LH) and follicle-stimulating hormone (FSH)
  • Suppress the production of estrogen and testosterone
Use:
  • Prostate cancer
  • Breast cancer
  • Endometriosis
  • Uterine fibroids
  • Precocious puberty
  • Gender dysphoria
Side Effects:
  • Hot flashes
  • Decreased libido
  • Erectile dysfunction
  • Vaginal dryness
  • Bone loss
  • Depression
  • Fatigue
Contraindications:
  • Pregnancy
  • Breastfeeding
  • Severe liver disease
  • Hypersensitivity to GnRH analogues
Specialty:
  • Oncology
  • Endocrinology
  • Obstetrics and gynecology
  • Pediatrics