Drug Name: | GnRH analogues |
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Drug Class: | Hormonal therapy |
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Mechanism of Action: | - Bind to GnRH receptors in the pituitary gland
- Reduce the secretion of luteinizing hormone (LH) and follicle-stimulating hormone (FSH)
- Suppress the production of estrogen and testosterone
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Use: | - Prostate cancer
- Breast cancer
- Endometriosis
- Uterine fibroids
- Precocious puberty
- Gender dysphoria
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Side Effects: | - Hot flashes
- Decreased libido
- Erectile dysfunction
- Vaginal dryness
- Bone loss
- Depression
- Fatigue
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Contraindications: | - Pregnancy
- Breastfeeding
- Severe liver disease
- Hypersensitivity to GnRH analogues
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Specialty: | - Oncology
- Endocrinology
- Obstetrics and gynecology
- Pediatrics
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